Posachedwapa, zimphona ziwiri zazikuluzikulu za fodya, PMI ndi BAT, zidasindikiza zofufuza m'magazini apamwamba azachipatala padziko lonse lapansi.Zotsatira za kafukufuku zikusonyeza kuti fodya watsopano monga e-fodya ndi kutentha-osawotcha ndi zochepa zovulaza komanso zapoizoni kusiyana ndi ndudu zachikhalidwe, ndipo zingathe kuchepetsa kwambiri zotsatira za kupuma.kuvulaza.
Pamene kuzindikira kwa anthu za kuopsa kwa kusuta kukukulirakulira, ndudu za e-fodya zikuzindikiridwa mowonjezereka ndi anthu monga choloŵa m’malo mwa ndudu.Komabe, kwa nthawi yaitali zotsatira za flavorede-fodyazosakaniza zokometsera ndi utsi wa ndudu pa osuta zikuyenera kufufuzidwanso.
Posachedwapa, PMI Philip Morris International adafalitsa lipoti la kafukufuku "Kuwunika kwa poizoni wa fodya wa ndudu ndi aerosols kuchokera ku zosakaniza zokometsera: Kuphunzira kwa masabata a 5 mu A / J mbewa" mu British Journal of Toxicology "Journal of Applied Toxicolog", kufotokoza mwatsatanetsatane. za mitu yokhudzana ndi kafukufuku ndi zotsatira zake.
Poyesera, mbewa zamphongo za 87 ndi 174 nulliparous ndi mbewa zazikazi zoyembekezera zinaperekedwa mwachisawawa kumagulu oyesera a 9, ndipo amachitidwa mumlengalenga, utsi wa ndudu, ndi ma aerosols a e-fodya okhala ndi mitundu itatu yosiyanasiyana ya zokometsera, zapamwamba, zapakati, ndi zochepa.Kuwonetsedwa kwa maola 6 patsiku, masiku asanu pa sabata, kwa milungu isanu kumatsatiridwa ndi necropsy, kulemera kwa ziwalo ndi kuwunika kwa histopathological.
Chithunzichi chikuwonetsa deta yowunika ya kutupa kwa mapapo a mbewa.Zitha kuwoneka kuti zofunikira za mbewa zomwe zimakhudzidwa ndi utsi wa ndudu zimakhala ndi yankho lodziwika bwino (gawo lofiira)
Zotsatira zomaliza zoyeserera zidawonetsa kuti mbewa zikawonetsedwa ndi e-fodya ya e-fodya yokhala ndi zokometsera komanso zopanda zokometsera, poyerekeza ndi zomwe zimakhudzidwa ndi utsi wa ndudu, panalibe kusintha kwakukulu kwa ziwalo zopuma, mphuno, ndi laryngeal epithelial tissues, zomwe zimasonyeza kuti e-fodya. The sol ndi zosakwiyitsa lolingana zimakhala ndi ziwalo.Zotsatira zoyesera zimatsimikiziranso kuti, poyerekeza ndi ndudu zachikhalidwe,e-nduduakhoza kuchepetsa kwambiri kutupa m'mapapo, komanso kuwonongeka kwa mphuno, mmero ndi tracheal epithelium.
BAT British American Fodya idasindikiza pepala lofufuzira lotchedwa "An Experimental Analytical and In Vitro Approach to Bridge Pakati pa Mitundu Yosiyanasiyana ya Fodya Yotentha" mu "Zopereka ku Fodya & Nicotine Research" magazini yasayansi, ndipo idachita kafukufuku pa THP (HNB product) Toxicology. kuyesa.
Poyesera, ma aerosols ndi utsi wa ndudu wamitundu isanu ya THP ndi THP imodzi yoyambira idagwiritsidwa ntchito ngati malo oyesera, ndipo cytotoxicity idawunikidwa ndi kuthekera kwa maselo am'mapapo amunthu.Zotsatira zinawonetsa kuti machitidwe onse a cytotoxic mu gulu la THP anali otsika pafupifupi 95% poyerekeza ndi omwe anali mu gulu la utsi wa ndudu, ndipo panalibe kusiyana kwakukulu kwa kawopsedwe pakati pa ma THP asanu osiyanasiyana ndi THP yoyambira.
Malinga ndi kafukufukuyu, chitukuko ndi kuperekedwa kwa mitundu ina ya fodya ndi chikonga zikukula mofulumira, ogula akuvomereza kwambiri zinthu zatsopano monga THP, ndipo chitetezo chake ndi chiopsezo monga gawo la kuwunika kwa toxicological ndizoyenera kuyang'anitsitsa makampani.Pokhapokha pamene mankhwalawo akwaniritsa miyezo (kuphatikizapo machitidwe a batri) angagwire bwino ntchito yake ngati njira yaumoyo wa anthu.
Maumboni
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, et al.Kuunikira kwa kawopsedwe ka utsi wa ndudu ndi ma aerosol kuchokera ku zosakaniza zokometsera: Kafukufuku wamasabata 5 mu mbewa za A/J.Journal of Applied Toxicolog, 2022
Tomasz Jaunky, David Thorne, Andrew Baxter, et al.Njira Yoyeserera ndi In Vitro Yofikira Mlatho Pakati pa Mitundu Yosiyanasiyana ya Fodya Wotentha.Zothandizira pa Fodya & Nicotine Research, 2022
Nthawi yotumiza: Dec-16-2022
